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Proteintech
OXCT1 Polyclonal Antibody
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Product Details
12175-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
OXCT1 Fusion Protein Ag2818 (151-520 aa encoded by BC009001)
Conjugate
Form
Liquid
Concentration
0.25 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
This antibody specifically recognizes endogenous OXCT1.
Immunogen sequence: GVPAFYTPT GYGTLVQEGG SPIKYNKDGS VAIASKPREV REFNGQHFIL EEAITGDFAL VKAWKADRAG NVIFRKSARN FNLPMCKAAE TTVVEVEEIV DIGAFAPEDI HIPQIYVHRL IKGEKYEKRI ERLSIRKEGD GEAKSAKPGD DVRERIIKRA ALEFEDGMYA NLGIGIPLLA SNFISPNITV HLQSENGVLG LGPYPRQHEA DADLINAGKE TVTILPGASF FSSDESFAMI RGGHVDLTML GAMQVSKYGD LANWMIPGKM VKGMGGAMDL VSSAKTKVVV TMEHSAKGNA HKIMEKCTLP LTGKQCVNRI ITEKAVFDVD KKKGLTLIEL WEGLTVDDVQ KSTGCDFAVS PKLMPMQQIA N (151-520 aa encoded by BC009001)
Target Information
This gene encodes a member of the 3-oxoacid CoA-transferase gene family. The encoded protein is a homodimeric mitochondrial matrix enzyme that plays a central role in extrahepatic ketone body catabolism by catalyzing the reversible transfer of coenzyme A from succinyl-CoA to acetoacetate. Mutations in this gene are associated with succinyl CoA:3-oxoacid CoA transferase deficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 3-oxoacid CoA transferase 1; 3-oxoacid CoA-transferase 1; 3-oxoacid-CoA transferase 1; oxct1 {ECO:0000312|EMBL:AAI66478.1}; SCOT; SCOT-s; somatic-type succinyl CoA:3-oxoacid CoA-transferase; Somatic-type succinyl-CoA:3-oxoacid CoA-transferase; somatic-type succinyl-CoA:3-oxoacid-CoA-transferase; succinyl CoA:3-oxoacid CoA transferase; succinyl-CoA:3-ketoacid CoA transferase; Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial; succinyl-CoA:3-ketoacid-CoA transferase; succinyl-CoA:3-ketoacid-coenzyme A transferase 1, mitochondrial; Succinyl-CoA:3-oxoacid CoA transferase
Gene Aliases: 2610008O03Rik; OXCT; OXCT1; Oxct2a; SCOT; Scot-s
UniProt ID: (Human) P55809, (Mouse) Q9D0K2, (Rat) B2GV06
Entrez Gene ID: (Human) 5019, (Mouse) 67041, (Rat) 690163
brain development
heart development
response to nutrient
response to hormone
response to activity
positive regulation of insulin secretion involved in cellular response to glucose stimulus
ketone catabolic process
response to drug
response to starvation
response to ethanol
cellular ketone body metabolic process
ketone body catabolic process
adipose tissue development
metabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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