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|Tested species reactivity||Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to residues C(14) R L Y E L L H G A G N H A A G I L T L(33) of Bovin Orexin A, conjugated to KLH.|
|Storage buffer||whole serum|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (IHC)||1:1,000 - 1:2000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-18310 detects Orexin A from rat samples.
PA1-18310 has been successfully used in immunohistochemistry procedures.
The PA1-18310 immunogen is a synthetic peptide corresponding to residues C(14) R L Y E L L H G A G N H A A G I L T L(33) of Bovin Orexin A, conjugated to KLH.
After reconstitution keep aliquots at -20°C for a higher stability, and at 4°C with an appropriate antibacterial agent. Glycerol (1:1) may be added for an additional stability. Avoid repetitive freeze/thaw cycles.
Reconstitute with 100 ul of distilled water.
Neuropeptides that play a significant role in the regulation of food intake and sleep-wakefulness, possibly by coordinating the complex behavioral and physiologic responses of these complementary homeostatic functions. A broader role in the homeostatic regulation of energy metabolism, autonomic function, hormonal balance and the regulation of body fluids, is also suggested. Orexin-A binds to both OX1R and OX2R with a high affinity, whereas orexin-B binds only to OX2R with a similar high affinity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Hcrt1; Hypocretin (orexin) neuropeptide; Hypocretin-1; orexin
Hcrt; orexin-A; Ox; Ppox