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Orexin R2 Polyclonal Antibody
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FIGURE: 1 / 5
Orexin R2 Antibody (OSO00050W-100UL) in IHC (P)
IHC on paraffin sections of rat spinal cord tissue using Rabbit antibody to Orexin R2: OSO00050W. HIER: 1 mM EDTA, pH 8 for 20 min using Thermo PT Module. Blocking: 0.2% LFDM in TBST filtered thru 0.2 µm. Detection was done using Novolink HRP polymer from Leica following manufacturers instructions. Primary antibody: dilution 1:1000, incubated 30 min at RT (using Autostainer). Sections were counterstained wi... View More
Product Details
OSO00050W-100UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ Ig
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide from c-terminal region of mouse Orexin receptor 2 (Ox2r) conjugated to an immunogenic carrier protein was used as the antigen
Conjugate
Form
Lyophilized
Concentration
Conc. Not Determined
Storage buffer
whole serum
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
The peptide is homologous in human and rat.
Specificity of this antibody: Orexin R2.
Target Information
The protein encoded by this gene is a G-protein coupled receptor involved in the regulation of feeding behavior. The encoded protein binds the hypothalamic neuropeptides orexin A and orexin B. A related gene encodes a G-protein coupled receptor that selectively binds orexin A.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: HCRTR1; hypocretin (orexin) receptor 2; hypocretin receptor 2; Hypocretin receptor type 2; orexin receptor 1; orexin receptor 2; Orexin receptor type 2; orexin receptor-1; orexin receptor-2; orexin type-2 receptor; OTTHUMP00000039969; Ox-2-R; OX1R; ox2-R; ox2r; unnamed protein product
Gene Aliases: HCRTR2; mOX2aR; mOX2bR; Mox2r; mOXR2; ORXR2; OX2R; OXR2
UniProt ID: (Human) O43614, (Rat) P56719, (Mouse) P58308
Entrez Gene ID: (Human) 3062, (Rat) 25605, (Mouse) 387285
signal transduction
G-protein coupled receptor signaling pathway
phospholipase C-activating G-protein coupled receptor signaling pathway
neuropeptide signaling pathway
chemical synaptic transmission
feeding behavior
regulation of circadian sleep/wake cycle, wakefulness
circadian sleep/wake cycle process
cellular response to hormone stimulus
locomotion
regulation of cytosolic calcium ion concentration
regulation of circadian sleep/wake cycle, sleep
response to peptide
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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