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Oxytocin Polyclonal Antibody
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FIGURE: 1 / 3
Oxytocin Antibody (PA5-26701) in IHC (P)
Immunohistochemistry analysis of Oxytocin in formalin fixed and paraffin embedded brain tissue. Samples were incubated with Oxytocin polyclonal antibody (Product # PA5-26701) followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of this antibody for immunohistochemistry. Clinical relevance has not been evaluated.
Product Details
PA5-26701
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Bovine
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 11-40 amino acids from the central region of human NEU1
Conjugate
Form
Liquid
Concentration
2 mg/mL
Amount
800 µg
Purification
Ammonium sulfate precipitation, Size-exclusion - Dialysis
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
There are two proteins encoded by this gene, oxytocin and neurophysin I. Oxytocin is posterior pituitary hormone which is synthesized as an inactive precursor in the hypothalamus along with its carrier protein neurophysin I. Together with neurophysin, it is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis, where it is either stored or secreted into the bloodstream. The precursor seems to be activated while it is being transported along the axon to the posterior pituitary. This hormone contracts smooth muscle during parturition and lactation. It is also involved in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: neurophysin I; OT-NPI; oxytocin, prepro- (neurophysin I); oxytocin, prepropeptide; Oxytocin-neurophysin 1; oxytocin-neurophysin I, preproprotein
Gene Aliases: OT; OT-NPI; OXT; OXT-NPI
UniProt ID: (Human) P01178
Entrez Gene ID: (Human) 5020
response to amphetamine
regulation of heart rate
maternal aggressive behavior
signal transduction
positive regulation of cytosolic calcium ion concentration
heart development
female pregnancy
memory
grooming behavior
response to sucrose
positive regulation of norepinephrine secretion
response to activity
response to food
positive regulation of prostaglandin secretion
response to estradiol
response to retinoic acid
response to progesterone
response to genistein
response to prostaglandin E
social behavior
intracellular signal transduction
negative regulation of urine volume
response to cocaine
maternal behavior
sperm ejaculation
eating behavior
drinking behavior
response to peptide hormone
response to ether
negative regulation of blood pressure
positive regulation of blood pressure
positive regulation of ossification
positive regulation of female receptivity
response to steroid hormone
positive regulation of synaptic transmission
response to glucocorticoid
response to cAMP
response to electrical stimulus
positive regulation of synapse assembly
male mating behavior
positive regulation of penile erection
positive regulation of hindgut contraction
positive regulation of uterine smooth muscle contraction
positive regulation of cold-induced thermogenesis
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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