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Invitrogen
P2Y1 Polyclonal Antibody
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Product Details
PA5-34071
Product Specifications
Species Reactivity
Bat,
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic 15 amino acid peptide from 2nd extracellular domain of human P2RY1 / P2Y1.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
50 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.1% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Marmoset, Bat (100%).
Target Information
P2Y1 is a Purinergic Receptor that causes a change in platelet shape and potentially leads to platelet aggregation by binding ADP, which results in the mobilization of intracellular calcium ions via activation of phospholipase C. This receptor also mediates the release of the relaxing factor nitric oxide and may be involved in the modulation of neuronal signal transmission. P2Y1 has been reported to be expressed in tissues throughout the body, particularly brain. ESTs have been isolated from human embryo, lung, and placenta libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ADP receptor; ATP receptor; P2 purinoceptor subtype Y1; P2Y purinoceptor 1; p2y-1-r; P2Y1; p2y1r; platelet ADP receptor; Purinergic receptor; purinergic receptor P2Y, G-protein coupled, 1; Purinoceptor p2y1; Purinoceptor p2yr1; suppressing androgen receptor in renal cell carcinoma; unnamed protein product
Gene Aliases: P2RY1; P2Y1; SARCC
UniProt ID: (Human) P47900
Entrez Gene ID: (Human) 5028
nucleotide binding
ADP receptor activity
G-protein coupled receptor activity
protein binding
ATP binding
receptor regulator activity
A1 adenosine receptor binding
signaling receptor activity
ADP binding
G-protein coupled purinergic nucleotide receptor activity
ATP-activated adenosine receptor activity
protein heterodimerization activity
scaffold protein binding
adenosine receptor signaling pathway
ion transport
signal transduction
cell surface receptor signaling pathway
G-protein coupled receptor signaling pathway
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
phospholipase C-activating G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
blood coagulation
hemostasis
glial cell migration
regulation of cell shape
response to mechanical stimulus
negative regulation of norepinephrine secretion
signal transduction involved in regulation of gene expression
platelet activation
positive regulation of inositol trisphosphate biosynthetic process
G-protein coupled purinergic nucleotide receptor signaling pathway
eating behavior
positive regulation of ion transport
positive regulation of transcription from RNA polymerase II promoter
positive regulation of hormone secretion
establishment of localization in cell
positive regulation of penile erection
positive regulation of ERK1 and ERK2 cascade
response to growth factor
cellular response to ATP
cellular response to purine-containing compound
protein localization to plasma membrane
relaxation of muscle
regulation of blood vessel diameter
regulation of presynaptic cytosolic calcium ion concentration
regulation of synaptic vesicle exocytosis
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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