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Invitrogen
P2Y6 Polyclonal Antibody
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FIGURE: 1 / 1
P2Y6 Antibody (PA5-109850) in WB
Western blot analysis of P2Y6 in extracts of Mouse lung. Samples were incubated with P2Y6 Polyclonal antibody (Product # PA5-109850) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.
Product Details
PA5-109850
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 200-300 of human Purinergic Receptor P2Y6 (NP_7897661)
Conjugate
Form
Liquid
Concentration
1.52 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: GFLLPFAALL ACYCLLACRL CRQDGPAEPV AQERRGKAAR MAVVVAAAFA ISFLPFHITK TAYLAVRSTP GVPCTVLEAF AAAYKGTRPF ASANSVLDPI L
Target Information
P2Y6 belongs to the family of G protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is responsive to UDP, partially responsive to UTP and ADP, and not responsive to ATP. P2Y6 expression has been documented in various blood cells, bone marrow, brain, colon, heart, kidney, ovary, placenta, spleen and thymus. ESTs have been isolated from cervix, embryo, eye, kidney, liver/spleen, placenta, and vessel libraries.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: G-coupled nucleotide receptor; MGC15335; P2 purinoceptor; P2Y purinoceptor 6; p2y3 and chick; p2y3 receptor; P2Y6; P2Y6 receptor; Purinoceptor p2y6; pyrimidinergic receptor P2Y, G-protein coupled, 6
Gene Aliases: 2010204J23Rik; P2RY6; P2Y6; PP2891
UniProt ID: (Human) Q15077, (Mouse) Q9ERK9
Entrez Gene ID: (Human) 5031, (Mouse) 233571
phospholipase C-activating G-protein coupled receptor signaling pathway
positive regulation of smooth muscle cell migration
transepithelial chloride transport
G-protein coupled purinergic nucleotide receptor signaling pathway
cellular response to prostaglandin E stimulus
cellular response to organic cyclic compound
signal transduction
G-protein coupled receptor signaling pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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