Peptide sequence: PTAMGSFSSH MTEFPRKRKG SDSDPSQSGI MTEKVVEKLS QNPLTYLLST
Sequence homology: Dog: 86%; Human: 100%; Mouse: 77%
ARNTL2-CLOCK heterodimers activate E-box element (3'-CACGTG-5') transcription. Also, in umbilical vein endothelial cells, ARNTL2 activates SERPINE1 through E-box sites. This transactivation is inhibited by PER2 and CRY1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: aryl hydrocarbon receptor nuclear translocator-like 2; Aryl hydrocarbon receptor nuclear translocator-like protein 2; Basic-helix-loop-helix-PAS protein MOP9; bHLHe6; Brain and muscle ARNT-like 2; brain-muscle-ARNT-like protein 2; Class E basic helix-loop-helix protein 6; CLIF; CYCLE-like factor; Member of PAS protein 9; PAS domain-containing protein 9; transcription factor BMAL2
Gene Aliases: 4632430A05Rik; ARNTL2; BHLHE6; BMAL2; CLIF; MOP9; PASD9