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This target displays homology in the following species: Human: 100%
The protein encoded by this gene is a membrane-bound type II serine polyprotease that is cleaved to release three different proteases. Two of the proteases are active and can be inhibited by serine protease inhibitors, and one is thought to be catalytically inactive. This gene enhances the invasive capability of pancreatic cancer cells and may be involved in cancer progression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: polyserase 1; Polyserase-1; Polyserase-I; Polyserine protease 1; Transmembrane protease serine 9; transmembrane serine protease 9
Gene Aliases: TMPRSS9
UniProt ID: (Human) Q7Z410
Entrez Gene ID: (Human) 360200
Molecular Function: serine protease
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