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Immunogen sequence: LQKLKARSFH GSQRGAELQP SRPTSLSQDS PRSLHTPSLR PSDVVQVSLK FKLLDPPNMG QDICFVLLAL NMSSQFKDLK VNLSAQSLLH DGSPLSPFWQ DTAFITLSPK EAKTYPCKIS YSQYSQYLST DKLIRISALG EEKSSPEKIL VNKIITLSYP SITINVLGAA VVNQPLSIQV IFSNPLSEQV EDCVLTVEGS GLFKKQQKVF LGVLKPQHQA SIILETVPFK SGQRQIQANM RSNKFKDIKG YRNVYVDFAL; Positive Samples: Mouse liver, Mouse heart, Rat liver, Rat heart; Cellular Location: Cytoplasm
This gene encodes a member of the transglutaminase family. The encoded protein catalyzes formation of protein cross-links between glutamine and lysine residues, often resulting in stabilization of protein assemblies. This reaction is calcium dependent. Mutations in this gene have been associated with acral peeling skin syndrome.
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Protein Aliases: MGC141907; Protein-glutamine gamma-glutamyltransferase 5; TG(X); TGase 5; TGase X; TGase-5; transglutaminase V; Transglutaminase X; Transglutaminase-5
Gene Aliases: 2310007C07Rik; PSS2; TGASE5; TGASEX; TGM5; TGM6; TGMX; TGX
UniProt ID: (Human) O43548, (Mouse) Q9D7I9
Entrez Gene ID: (Human) 9333, (Mouse) 74176
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