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Invitrogen
PACAP-38 (Biosimilar) Recombinant Human Monoclonal Antibody
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Product Details
MA5-58905
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Human
/ IgG1
Expression System
CHO cells
Class
Recombinant Monoclonal
Type
Antibody
Conjugate
Form
Lyophilized
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
25mM histidine, pH 6.2, with 8% sucrose, 0.01% Tween 80
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Dry ice (international)
RRID
Product Specific Information
For reconstitution, add sterile, distilled water to achieve a final antibody concentration of 1 mg/mL. Gently shake to solubilize the protein completely. Do not vortex. Reconstituted products should be stored at -80 °.
This antibody can also be cross referenced by the term Lilly patent anti-PACAP.
Target Information
Binding to its receptor activates G proteins and stimulates adenylate cyclase in pituitary cells. Promotes neuron projection development through the RAPGEF2/Rap1/B-Raf/ERK pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: adenylate cyclase activating polypeptide 1 (pituitary); PACAP; Pituitary adenylate cyclase-activating polypeptide; prepro-PACAP; unnamed protein product
Gene Aliases: ADCYAP1; PACAP
UniProt ID: (Human) P18509
Entrez Gene ID: (Human) 116
adenylate cyclase-modulating G-protein coupled receptor signaling pathway
adenylate cyclase-activating G-protein coupled receptor signaling pathway
activation of adenylate cyclase activity
positive regulation of cytosolic calcium ion concentration
neuropeptide signaling pathway
cell-cell signaling
nervous system development
female pregnancy
regulation of G-protein coupled receptor protein signaling pathway
positive regulation of gene expression
insulin secretion
neuron projection development
regulation of protein localization
positive regulation of GTPase activity
negative regulation of cell cycle
positive regulation of protein kinase activity
positive regulation of transcription from RNA polymerase II promoter
positive regulation of growth hormone secretion
positive regulation of ERK1 and ERK2 cascade
positive regulation of chemokine (C-C motif) ligand 5 production
positive regulation of cold-induced thermogenesis
positive regulation of cAMP/PKA signal transduction
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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