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PACRG Polyclonal Antibody
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Product Details
BS-9289R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human PACRG.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
PACRG is a protein that is conserved across metazoans. In vertebrates, this gene is linked in a head-to-head arrangement with the adjacent parkin gene, which is associated with autosomal recessive juvenile Parkinson's disease. These genes are co-regulated in various tissues and they share a bi-directional promoter. Both genes are associated with susceptibility to leprosy. The parkin co-regulated gene protein forms a large molecular complex with chaperones, including heat shock proteins 70 and 90, and chaperonin components. This protein is also a component of Lewy bodies in Parkinson's disease patients, and it suppresses unfolded Pael receptor-induced neuronal cell death.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ32724; Hypertension-related protein 1-like protein; Molecular chaperone/chaperonin-binding protein; PARK2 co-regulated; PARK2 coregulated; PARK2 coregulated gene protein; Parkin co-regulated gene protein; Parkin coregulated gene protein; Parkin coregulated gene protein homolog; RP3-495O10.2; unnamed protein product
Gene Aliases: 1700008H23Rik; BUG21; GLUP; HAK005771; PACRG; PACRG2.1; PARK2CRG; pf12; RGD1561027
UniProt ID: (Human) Q96M98, (Mouse) Q9DAK2
Entrez Gene ID: (Human) 135138, (Mouse) 69310, (Rat) 499021
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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