Immunogen sequence: MSQSRHRAE APPLEREDSG TFSLGKMITA KPGKTPIQVL HEYGMKTKNI PVYECERSDV QIHVPTFTFR VTVGDITCTG EGTSKKLAKH RAAEAAINIL KANASICFAV PDPLMPDPSK QPKNQLNPIG SLQELAIHHG WRLPEYTLSQ EGGPAHKREY TTICRLESFM ETGKGASKKQ AKRNAAEKFL AKFSNISPEN HISLTNVVGH SLGCTWHSLR NSPGEKINLL KRSLLSIPNT DYIQLLSEIA KEQGFNITYL DIDELSANGQ YQCLAELSTS PITVCHGSGI SCGNAQSDAA HNALQYLKII AERK (1-313 aa encoded by BC009470)
PRKRA appears to have a pro-apoptotic function that may be suppressed in the presence of growth factor. It activates EIF2AK2 in the absence of double-stranded RNA (dsRNA).
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Protein Aliases: interferon-inducible double stranded RNA-dependent protein kinase activator A; Interferon-inducible double-stranded RNA-dependent protein kinase activator A; PKR associated protein X; PKR-associated protein X; PKR-associating protein X; Protein activator of the interferon-induced protein kinase; protein kinase, interferon-inducible double stranded RNA dependent activator; protein kinase, interferon-inducible double stranded RNA-dependent activator; Protein kinase, interferon-inducible double-stranded RNA-dependent activator; RAX
Gene Aliases: AV120107; DYT16; HSD-14; HSD14; lear; PACT; PRK; PRKRA; RAX