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Proteintech
PACT Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
10771-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PACT Fusion Protein Ag1214 (1-313 aa encoded by BC009470)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.17 mg/mL
Amount
25.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MSQSRHRAE APPLEREDSG TFSLGKMITA KPGKTPIQVL HEYGMKTKNI PVYECERSDV QIHVPTFTFR VTVGDITCTG EGTSKKLAKH RAAEAAINIL KANASICFAV PDPLMPDPSK QPKNQLNPIG SLQELAIHHG WRLPEYTLSQ EGGPAHKREY TTICRLESFM ETGKGASKKQ AKRNAAEKFL AKFSNISPEN HISLTNVVGH SLGCTWHSLR NSPGEKINLL KRSLLSIPNT DYIQLLSEIA KEQGFNITYL DIDELSANGQ YQCLAELSTS PITVCHGSGI SCGNAQSDAA HNALQYLKII AERK (1-313 aa encoded by BC009470)
Target Information
PRKRA appears to have a pro-apoptotic function that may be suppressed in the presence of growth factor. It activates EIF2AK2 in the absence of double-stranded RNA (dsRNA).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: dsRNA-binding protein; PKR associated protein X; PKR interacting protein; PKR-associated protein X; PKR-associating protein X; PRKRA; protein activator of the interferon-induced protein kinase; protein kinase, interferon-inducible double-stranded RNA-dependent activator; unnamed protein product
Gene Aliases: DYT16; HSD14; lear; PACT; PRK; RAX
UniProt ID: (Human) O75569, (Mouse) Q9WTX2, (Rat) Q4V8C7
Entrez Gene ID: (Human) 8575, (Mouse) 23992, (Rat) 311130
immune response
negative regulation of cell proliferation
response to virus
production of siRNA involved in RNA interference
pre-miRNA processing
production of miRNAs involved in gene silencing by miRNA
protein stabilization
regulation of production of small RNA involved in gene silencing by RNA
small RNA loading onto RISC
antiviral innate immune response
protein phosphorylation
positive regulation of cell proliferation
cellular response to oxidative stress
outer ear morphogenesis
middle ear morphogenesis
ear development
skeletal system morphogenesis
positive regulation of intrinsic apoptotic signaling pathway
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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