This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. This protein may play a role in cytoskeletal reorganization in the egg and in early embryo development.
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Protein Aliases: Arginine deiminase-like protein; Egg and embryo abundant PAD; ePAD; hPADVI; peptidyl arginine deiminase, egg and embryo abundant; peptidyl arginine deiminase, type VI; Peptidyl arginine deiminase-like protein; peptidylarginine deiminase type 6; Peptidylarginine deiminase VI; Protein-arginine deiminase type VI; Protein-arginine deiminase type-6
Gene Aliases: ePAD; hPADVI; PAD6; Padi5; PADI6
Molecular Function: hydrolase