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Invitrogen
PAM Polyclonal Antibody
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Product Details
PA5-59929
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human PAM. Recombinant protein control fragment (Product #RP-88689).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: HLGKVVSGYR VRNGQWTLIG RQSPQLPQAF YPVGHPVDVS FGDLLAARCV FTGEGRTEAT HIGGTSSDEM CNLYIMYYME AKHAVSFMTC TQNVAPDMFR TIPPEANIPI PVKSDMVMMH EHHKETEYKD KIPLLQQPKR EEEEVL
Highest antigen sequence identity to the following orthologs: Mouse - 90%, Rat - 88%.
Target Information
SNX33 (sorting nexin-33), also known as SH3PX3, SH3PXD3C or SNX30, is a 574 amino acid protein that interacts with ADAM15 and FAS-L. Belonging to the sorting nexin family, SNX33 contains one BAR domain, one PX (phox homology) domain and one SH3 domain. The gene that encodes SNX33 consists of over 14,000 bases and maps to human chromosome 15q24.2. Housing approximately 106 million base pairs and encoding more than 700 genes, chromosome 15 makes up about 3% of the human genome. Angelman and Prader-Willi syndromes are associated with loss of function or deletion of genes in the 15q11-q13 region.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: PAM; pancreatic peptidylglycine alpha-amidating monooxygenase; peptidyl alpha-amidating enzyme; peptidyl-alpha-hydroxyglycine alpha-amidating lyase; Peptidyl-glycine alpha-amidating monooxygenase; peptidylamidoglycolate lyase; peptidylglycine 2-hydroxylase; peptidylglycine alpha-hydroxylating monooxygenase
Gene Aliases: PAL; PAM; PHM
UniProt ID: (Human) P19021
Entrez Gene ID: (Human) 5066
peptide amidation
response to hypoxia
long-chain fatty acid metabolic process
regulation of transcription from RNA polymerase II promoter
central nervous system development
heart development
lactation
response to pH
toxin metabolic process
protein amidation
ovulation cycle process
response to estradiol
regulation of actin cytoskeleton organization
odontogenesis
response to drug
response to copper ion
regulation of protein secretion
protein homooligomerization
response to glucocorticoid
oxidation-reduction process
maternal process involved in female pregnancy
limb development
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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