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Proteintech
PAPPA Polyclonal Antibody
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Product Details
18095-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PAPPA fusion protein Ag11863
Conjugate
Form
Liquid
Concentration
0.55 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: ACEPVDCSIP DHHQVYAASF SCPEGTTFGS QCSFQCRHPA QLKGNNSLLT CMEDGLWSFP EALCELMCLA PPPVPNADLQ TARCRENKHK VGSFCKYKCK PGYHVPGSSR KSKKRAFKTQ CTQDGSWQEG ACVPVTCDPP PPKFHGLYQC TNGFQFNSEC RIKCEDSDAS QGLGSNVIHC RKDGTWNGSF HVCQEMQGQC SVPNELNSNL KLQCPDGYAI GSECATSCLD HNSESIILPM NVTVRDIPHW LNPTRVERVV CTAGLKWYPH PALIHCVKGC EPFMGDNYCD AINNRAFCNY DGGDCCTSTV KTKKVTPFPM SCDLQGDCAC RDPQAQEHSR KDLQGYSHG
Target Information
Pregnancy-associated plasma protein-A (PAPP-A, Insulin-like growth factor binding protein-4 protease, PAPP-A-proMBP complex) is a large heterottetrameric glycoprotein of approximately 500 kDa, which was first discovered in serum from pregnant women. The hetreotetramer consists of two PAPP-A subunits and two proMBP subunits. Low maternal serum levels of PAPP-A in first trimester biochemical screening is used as a marker of Down's syndrome (trisomy 21).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: aspecific BCL2 ARE-binding protein 2; differentially placenta 1 expressed protein; IGF-dependent IGFBP-4 protease; IGFBP-4 ase; insulin-like growth factor-dependent IGF binding protein-4 protease; Insulin-like growth factor-dependent IGF-binding protein 4 protease; PAPP A; PAPP-A; Pappalysin; Pappalysin-1; pregnacy-associated plasma protein A; Pregnancy-associated plasma protein A; pregnancy-associated plasma protein A, pappalysin 1; RP11-45A16.1
Gene Aliases: ASBABP2; DIPLA1; IGFBP-4ase; PAPA; PAPP-A; PAPPA; PAPPA1
UniProt ID: (Human) Q08371
Entrez Gene ID: (Human) 5069
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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