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Proteintech
PARP9 Polyclonal Antibody
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Product Details
17535-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PARP9 Fusion Protein Ag11587 (476-819 aa encoded by BC039580)
Conjugate
Form
Liquid
Concentration
0.33 mg/mL
Amount
49.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: EARSPAINL MGFNVEEMYE AHAWIQRILS LQNHHIIENN HILYLGRKEH DILSQLQKTS SVSITEIISP GRTELEIEGA RADLIEVVMN IEDMLCKVQE EMARKKERGL WRSLGQWTIQ QQKTQDEMKE NIIFLKCPVP PTQELLDQKK QFEKCGLQVL KVEKIDNEVL MAAFQRKKKM MEEKLHRQPV SHRLFQQVPY QFCNVVCRVG FQRMYSTPCD PKYGAGIYFT KNLKNLAEKA KKISAADKLI YVFEAEVLTG FFCQGHPLNI VPPPLSPGAI DGHDSVVDNV SSPETFVIFS GMQAIPQYLW TCTQEYVQSQ DYSSGPMRPF AQHPWRGFAS GSPVD (476-819 aa encoded by BC039580)
Target Information
In concert with DTX3L plays a role in PARP1-dependent DNA damage repair. PARP1-dependent PARP9/BAL1-DTX3L-mediated ubiquitination promotes the rapid and specific recruitment of 53BP1/TP53BP1, UIMC1/RAP80, and BRCA1 to DNA damage sites. Involved in inducing the expression of IFN-gamma-responsive genes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: ADP-ribosyltransferase diphtheria toxin-like 9; ARTD9; B aggressive lymphoma protein; PARP-9; poly (ADP-ribose) polymerase 9; Poly [ADP-ribose] polymerase 9; Protein mono-ADP-ribosyltransferase PARP9; unnamed protein product
Gene Aliases: ARTD9; BAL; BAL1; MGC:7868; PARP9; RGD1307534
UniProt ID: (Human) Q8IXQ6
Entrez Gene ID: (Human) 83666, (Rat) 303905
transcription corepressor activity
NAD+ ADP-ribosyltransferase activity
enzyme inhibitor activity
protein binding
transferase activity
transferase activity, transferring glycosyl groups
nucleotidyltransferase activity
enzyme binding
histone binding
ubiquitin-like protein ligase binding
NAD+ binding
ADP-D-ribose binding
STAT family protein binding
NAD+-protein-C-terminal glycine ADP-ribosyltransferase activity
DNA damage checkpoint
negative regulation of transcription from RNA polymerase II promoter
positive regulation of cytokine-mediated signaling pathway
positive regulation of defense response to virus by host
immune system process
DNA repair
double-strand break repair
cellular response to DNA damage stimulus
posttranscriptional regulation of gene expression
negative regulation of gene expression
cell migration
viral protein processing
NAD salvage
positive regulation of chromatin binding
positive regulation of tyrosine phosphorylation of STAT protein
negative regulation of catalytic activity
innate immune response
positive regulation of transcription, DNA-templated
defense response to virus
regulation of response to interferon-gamma
regulation of interferon-gamma-mediated signaling pathway
positive regulation of interferon-gamma-mediated signaling pathway
protein poly-ADP-ribosylation
positive regulation of protein localization to nucleus
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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