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|Tested species reactivity||Mouse|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide sequence (REEKLRNQRRQASN) corresponding to the internal amino acids of PAX6|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||0.3-1 ug/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
This antibody is predicted to react with human and rat based on sequence homology.
This gene encodes paired box gene 6, one of many human homologs of the Drosophila melanogaster gene prd. In addition to the hallmark feature of this gene family, a conserved paired box domain, the encoded protein also contains a homeo box domain. Both domains are known to bind DNA, and function as regulators of gene transcription. This gene is expressed in the developing nervous system, and in developing eyes. Mutations in this gene are known to cause ocular disorders such as aniridia and Peter's anomaly. Alternatively spliced transcript variants encoding either the same or different isoform have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
AN; AN2; D11S812E; Dickie's small eye; MGC17209; MGDA; oculorhombin; paired box gene 6; paired box gene 6 (aniridia, keratitis); paired box homeotic gene 6 (aniridia, keratitis); paired box homeotic gene-6; paired box protein Pax-6; PAX6; small eye; WAGR
1500038E17Rik; AEY11; Dey; Gsfaey11; Pax-6; Pax6; Sey