Immunogen sequence: KFSHLPAKERQ TIVELAKMFL NRINYWHLEA PSQRRLRSPN DDISGYKENY
Highest antigen sequence identity to the following orthologs - mouse 94%, rat 59%.
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.
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Protein Aliases: CAF; CREBBP-associated factor; Histone acetylase PCAF; Histone acetyltransferase KAT2B; Histone acetyltransferase PCAF; K(lysine) acetyltransferase 2B; KAT2B; Lysine acetyltransferase 2B; P; P/CAF; P300/CBP-associated factor; PCAF; Spermidine acetyltransferase KAT2B
Gene Aliases: CAF; KAT2B; P/CAF; PCAF
UniProt ID: (Human) Q92831
Entrez Gene ID: (Human) 8850