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Proteintech
PCBD1 Polyclonal Antibody
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Product Details
15702-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PCBD1 Fusion Protein Ag8331 (1-104 aa encoded by BC006324)
Conjugate
Form
Liquid
Concentration
0.49 mg/mL
Amount
73.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MAGKAHRLS AEERDQLLPN LRAVGWNELE GRDAIFKQFH FKDFNRAFGF MTRVALQAEK LDHHPEWFNV YNKVHITLST HECAGLSERD INLASFIEQV AVSMT (1-104 aa encoded by BC006324)
Target Information
PCBD1 encodes pterin-4 alpha-carbinolamine dehydratase, an enzyme involved in phenylalanine hydroxylation. A deficiency of this enzyme leads to hyperphenylalaninemia. The enzyme regulates the homodimerization of the transcription factor hepatocyte nuclear factor 1 (HNF1).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 4-alpha-hydroxy-tetrahydropterin dehydratase; 6-pyruvoyl-tetrahydropterin synthase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1); DCoH; Dimerization cofactor of hepatocyte nuclear factor 1-alpha; dimerization cofactor of HNF1; dimerizing cofactor for HNF1; PCBD; PCD; PCD/DCoH; dimerization cofactor of HNF1; Phenylalanine hydroxylase-stimulating protein; PHS; pt; Pterin carbinolamine dehydratase; pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha; Pterin-4-alpha-carbinolamine dehydratase
Gene Aliases: DCOH; PCBD; PCBD1; PCD; PHS; TCF1
UniProt ID: (Human) P61457, (Mouse) P61458, (Rat) P61459
Entrez Gene ID: (Human) 5092, (Mouse) 13180, (Rat) 29700
tetrahydrobiopterin biosynthetic process
tyrosine biosynthetic process, by oxidation of phenylalanine
positive regulation of transcription, DNA-templated
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of protein homodimerization activity
protein homotetramerization
protein heterooligomerization
oxidation-reduction process
L-phenylalanine metabolic process
biological_process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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