|Tested species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 850 and 1040 of Human PCDH10|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 1% BSA, 20% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Western Blot (WB)||See 1 publications below|
PA5-31042 targets PCDH10 in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-31042 immunogen is recombinant fragment corresponding to a region within amino acids 850 and 1040 of Human PCDH10.
This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The mRNA encodes a cadherin-related neuronal receptor thought to play a role in the establishment and function of specific cell-cell connections in the brain. This family member contains 6 extracellular cadherin domains, a transmembrane domain and a cytoplasmic tail differing from those of the classical cadherins. Alternatively spliced transcripts encode isoforms with unique cytoplasmic domains.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
PCDH10, a novel p53 transcriptional target in regulating cell migration.
PA5-31042 was used in western blot to study the relationship between PCDH10 and p53 in cancer cells
|Shi D,Murty VV,Gu W||Cell cycle (Georgetown, Tex.) (14:857)||2015|