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Fabgennix
PDE1A Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PD1A-101AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to unique amino acid sequence within amino acid region 1-50 on PDE1A protein. Common to all PDE1A variants.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.5-1.5 mg/mL
Purification
Affinity chromatography
Storage buffer
proprietary buffer, pH 7.4-7.8, with 30% glycerol, 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Cyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and/or cGMP to their respective nucleoside 5-prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca(2+)/calmodulin (see CALM1)that are activated by calmodulin in the presence of Ca(2+) (Michibata et al., 2001).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 3'-RACE clone 8 phosphodiesterase 1A; 3-RACE clone 8 phosphodiesterase 1A; 61 kDa Cam-PDE; calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A; calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase; cam-PDE 1A; HS MGC26303; MGC26303; PDE1A; phosphodiesterase 1A, calmodulin-dependent; phosphodiesterase-1A; unnamed protein product
Gene Aliases: 3'-RACEclone8phosphodiesterase1A; 3-RACEclone8phosphodiesterase1A; CAM-PDE 1A; CAM-PDE-1A; HCAM-1; HCAM1; HSPDE1A
UniProt ID: (Human) P54750, (Mouse) Q61481
Entrez Gene ID: (Human) 5136, (Rat) 81529, (Mouse) 18573
3',5'-cyclic-nucleotide phosphodiesterase activity
3',5'-cyclic-AMP phosphodiesterase activity
calmodulin-dependent cyclic-nucleotide phosphodiesterase activity
protein binding
phosphoric diester hydrolase activity
3',5'-cyclic-GMP phosphodiesterase activity
calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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