The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE7 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
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Protein Aliases: HCP1; High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A; P2A; phosphodiesterase isozyme 7; rolipram-insensitive phosphodiesterase type 7; TM22
Gene Aliases: AU015378; AW047537; HCP1; PDE7; PDE7-1; PDE7A
Molecular Function: phosphodiesterase