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Invitrogen
PDGFRL Polyclonal Antibody
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Product Details
PA5-106500
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human PDGFRL(Accession Q15198), corresponding to amino acid residues A88-T138.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total PDGFRL.
Target Information
PDGFRL bears significant sequence similarity to the ligand binding domain of platelet-derived growth factor receptor beta. Mutations in the PDGFRL gene, or deletion of a chromosomal segment containing this gene, are associated with sporadic hepatocellular carcinomas, colorectal cancers, and non-small cell lung cancers. This suggests PDGFRL may function as a tumor suppressor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: PDGF receptor beta-like tumor suppressor; PDGFR-like protein; Platelet-derived growth factor receptor-like protein; platelet-derived growth factor-beta-like tumor suppressor
Gene Aliases: 1110039P19Rik; AV013190; PDGFRL; PDGRL; PRLTS
UniProt ID: (Human) Q15198, (Mouse) Q6PE55, (Rat) Q5RJP7
Entrez Gene ID: (Human) 5157, (Mouse) 68797, (Rat) 290771
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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