Immunogen sequence: RGFVYLQPHSE HQGVVYCRAE AGGRSQISVK YQLLYVAVPS GPPSTTILAS SNKVKSGDDI SVLCTVLGEP DVEVEFTWIF PGQKDERPVT IQDTWRLIHR GLGHTTRISQ SVITVEDFET IDAGYYICTA QNLQGQTTV
Highest antigen sequence identity to the following orthologs - mouse 93%, rat 94%.
PDGFRL bears significant sequence similarity to the ligand binding domain of platelet-derived growth factor receptor beta. Mutations in the PDGFRL gene, or deletion of a chromosomal segment containing this gene, are associated with sporadic hepatocellular carcinomas, colorectal cancers, and non-small cell lung cancers. This suggests PDGFRL may function as a tumor suppressor.
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Protein Aliases: PDGF receptor beta-like tumor suppressor; PDGFR-like protein; Platelet-derived growth factor receptor-like protein; platelet-derived growth factor-beta-like tumor suppressor; PRLTS
Gene Aliases: PDGFRL; PDGRL; PRLTS
UniProt ID: (Human) Q15198
Entrez Gene ID: (Human) 5157