Immunogen sequence: HGVCYTRGLS VRSILAELTG RRGGCAKGKG GSMHMYTKNF YGGNGIVGAQ GPLGAGIALA CKYKGNDEIC LTLYGDGAAN QGQIAEAFNM AALWKLPCVF ICENNLYGMG TSTERAAASP DYYKRGNFIP GLKVDGMDVL CVREATKFAA NYCRSGKGPI LMELQTYRYH GHSMSDPGVS YRTREEIQEV RSKRDPIIIL QDRMVNSKLA TVEELKEIGA EVRKEIDDAA QFATTDPEPH LEELGHHIYS SDSSFEVRGA NPWIKFKSVS; Positive Samples: NCI-H460, SKOV3, A549, Mouse testis, Mouse ovary; Cellular Location: Mitochondrion matrix
PDHA2 (Pyruvate Dehydrogenase E1 Alpha 2 Subunit) is a Protein Coding gene. Diseases associated with PDHA2 include Spermatogenic Failure 1. Among its related pathways are Citrate cycle (TCA cycle)and Central carbon metabolism in cancer. Gene Ontology (GO) annotations related to this gene include oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptorandpyruvate dehydrogenase (acetyl-transferring) activity. An important paralog of this gene isPDHA1.
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Protein Aliases: PDHE1-A type II; pyruvate dehydrogenase E1 alpha 2; PYRUVATE DEHYDROGENASE E1 COMPONENT ALPHA SUBUNIT, TESTIS-SPECIFIC FORM, MITOCHONDRIAL PRECURSOR (PDHE1-A TYPE II); Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial; pyruvate dehydrogenase, E1-alpha polypeptide, testis specific
Gene Aliases: Pdha-2; PDHA2; PDHAL