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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • PDHB Antibodies

          Invitrogen

          PDHB Polyclonal Antibody

          Advanced Verification
          1 Published Figure
          2 References
          View all (14) PDHB antibodies

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          Cite PDHB Polyclonal Antibody

          • Antibody Testing Data (8)
          • Published Figures (1)
          • Advanced Verification (2)
          PDHB Antibody in Immunocytochemistry (ICC/IF)
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          PDHB Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 11

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          PDHB Antibody (PA5-57793) in ICC/IF

          Immunofluorecent analysis of PDHB in human cell line U-2 OS using PDHB Polyclonal Antibody (Product # PA5-57793). Staining shows localization to mitochondria. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
          Published figure supplied by benchsci-logo
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          View Product

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          PDHB Antibody in Immunocytochemistry (ICC/IF)
          PDHB Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          PDHB Antibody in Immunohistochemistry (IHC)
          PDHB Antibody in Immunohistochemistry (IHC)
          PDHB Antibody in Immunohistochemistry (IHC)
          PDHB Antibody in Immunohistochemistry (IHC)
          PDHB Antibody in Immunohistochemistry (IHC)
          PDHB Antibody in Western Blot (WB)
          PDHB Antibody in Western Blot (WB)
          PDHB Antibody
          PDHB Antibody
          PDHB Polyclonal Antibody

          Product Details

          PA5-57793

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          0.04-0.4 µg/mL
          View 1 publication 1 publication

          Immunohistochemistry (Paraffin) (IHC (P))

          1:50-1:200
          -

          Immunocytochemistry (ICC/IF)

          0.25-2 µg/mL
          -

          Affinity Purification (AP)

          -
          View 1 publication 1 publication
          Product Specifications

          Species Reactivity

          Human

          Published species

          C. elegans

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein corresponding to Human PDHB. Recombinant protein control fragment (Product #RP-102743).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.2 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2645335

          Product Specific Information

          Immunogen sequence: LIKSAIRDNN PVVVLENELM YGVPFEFPPE AQSKDFLIPI GKAKIERQGT HITVVSHSRP VGHCLEAAAV LSKEGVE

          Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 91%.

          Target Information

          PDHB (Pyruvate dehydrogenase E1 component subunit beta, mitochondrial) is also named as PHE1B. The enzyme, which is found in mitochondria, is one of the component enzymes of the pyruvate dehydrogenase multienzyme complex (PDH). It catalyzes the first reaction of an oxidative decarboxylation sequence converting pyruvate to acetyl-CoA and CO(2). Defects in PDHB are the cause of pyruvate dehydrogenase E1-beta deficiency (PDHBD).

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: PDHE1-B; Pyruvate dehydrogenase E1 component subunit beta, mitochondrial; pyruvate dehydrogenase, E1 beta polypeptide

          View more View less

          Gene Aliases: PDHB; PDHBD; PDHE1-B; PHE1B

          View more View less

          UniProt ID: (Human) P11177

          View more View less

          Entrez Gene ID: (Human) 5162

          View more View less

          Function(s)
          pyruvate dehydrogenase activity pyruvate dehydrogenase (acetyl-transferring) activity protein binding pyruvate dehydrogenase (NAD+) activity dehydrogenase oxidoreductase metabolite interconversion enzyme
          Process(es)
          glucose metabolic process acetyl-CoA biosynthetic process from pyruvate pyruvate metabolic process tricarboxylic acid cycle regulation of acetyl-CoA biosynthetic process from pyruvate glyoxylate metabolic process mitochondrial acetyl-CoA biosynthetic process from pyruvate
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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          We're here to help

          Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

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