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Proteintech
PDK2 Polyclonal Antibody
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Product Details
15647-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PDK2 Fusion Protein Ag8183 (135-407 aa encoded by BC005811)
Conjugate
Form
Liquid
Concentration
0.13 mg/mL
Amount
19.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: LEYKDTYGD DPVSNQNIQY FLDRFYLSRI SIRMLINQHT LIFDGSTNPA HPKHIGSIDP NCNVSEVVKD AYDMAKLLCD KYYMASPDLE IQEINAANSK QPIHMVYVPS HLYHMLFELF KNAMRATVES HESSLILPPI KVMVALGEED LSIKMSDRGG GVPLRKIERL FSYMYSTAPT PQPGTGGTPL AGFGYGLPIS RLYAKYFQGD LQLFSMEGFG TDAVIYLKAL STDSVERLPV YNKSAWRHYQ TIQEAGDWCV PSTEPKNTST YRVS (135-407 aa encoded by B C005811)
Target Information
PDK2 inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial; [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2, mitochondrial; PDH kinase 2; PDK P45; pyruvate dehydrogenase; pyruvate dehydrogenase 2; pyruvate dehydrogenase kinase 2 subunit p45 (PDK2); Pyruvate dehydrogenase kinase isoform 2; pyruvate dehydrogenase kinase, isoenzyme 2; pyruvate dehydrogenase kinase, isozyme 2; pyruvate dehydrogenase, lipoamide, kinase isozyme 2, mitochondrial; unnamed protein product
Gene Aliases: PDHK2; PDK2; PDKII
UniProt ID: (Human) Q15119, (Rat) Q64536, (Mouse) Q9JK42
Entrez Gene ID: (Human) 5164, (Rat) 81530, (Mouse) 18604
nucleotide binding
protein kinase activity
pyruvate dehydrogenase (acetyl-transferring) kinase activity
protein binding
ATP binding
kinase activity
transferase activity
protein homodimerization activity
protein serine/threonine kinase activity
protein complex binding
protein heterodimerization activity
non-receptor serine/threonine protein kinase
glucose metabolic process
regulation of gluconeogenesis
regulation of pH
insulin receptor signaling pathway
regulation of acetyl-CoA biosynthetic process from pyruvate
regulation of cellular ketone metabolic process
regulation of glucose metabolic process
cellular response to nutrient
cellular response to stress
cellular response to reactive oxygen species
glucose homeostasis
regulation of calcium-mediated signaling
intrinsic apoptotic signaling pathway by p53 class mediator
protein phosphorylation
peptidyl-serine phosphorylation
carbohydrate metabolic process
phosphorylation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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