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Proteintech
CD357 (GITR) Monoclonal Antibody (DTA-1), PE
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FIGURE: 1 / 1
CD357 (GITR) Antibody (PE-65102-100UG) in Flow
1X10^6 Mouse splenocytes were surface stained with 0.06 µg APC-Anti-Mouse CD4 (APC-65104, clone GK1.5), 0.125 µg FITC-Anti-Mouse CD25 (FITC-65137, clone PC61.5) and 0.06 µg PE-Anti-Mouse CD357 (GITR) (Product # PE-65102-100UG), clone DTA-1). Cells were not fixed. CD4+ lymphocytes were gated for analysis ofCD25 and CD357 (GITR) staining.
Product Details
PE-65102-100UG
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Rat
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
DTA-1
Conjugate
Excitation/Emission Max
565/576 nm
View spectra
Form
Liquid
Concentration
0.2 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.2, with 0.1% gelatin
Contains
0.09% sodium azide
Storage conditions
4°C, store in dark
Shipping conditions
Wet ice
Target Information
Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), also called GITR or AITR is a protein that in humans is encoded by the TNFRSF18 gene. It is mapped to 1p36.33. This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25 (+)CD4 (+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CD357; Glucocorticoid-induced TNFR-related protein; PRO364; Tumor necrosis factor receptor superfamily member 18; UNQ319
Gene Aliases: AITR; Gitr; Tnfrsf18
UniProt ID: (Mouse) O35714
Entrez Gene ID: (Mouse) 21936
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