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Invitrogen
PEX7 Polyclonal Antibody
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Product Details
PA5-101744
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human PEX7(Accession O00628), corresponding to amino acid residues S277-A323.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total PEX7.
Target Information
This gene encodes the cytosolic receptor for the set of peroxisomal matrix enzymes targeted to the organelle by the peroxisome targeting signal 2 (PTS2). Defects in this gene cause peroxisome biogenesis disorders (PBDs), which are characterized by multiple defects in peroxisome function. There are at least 14 complementation groups for PBDs, with more than one phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene have been associated with PBD complementation group 11 (PBD-CG11) disorders, rhizomelic chondrodysplasia punctata type 1 (RCDP1), and Refsum disease (RD).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: PCDP1; Peroxin 7; Peroxin-7; peroxisomal biogenesis factor 7; peroxisomal PTS2 receptor; Peroxisomal targeting signal 2 receptor; peroxisome biogenesis factor 7; peroxisome targeting signal 2 receptor; PEX7 protein; PTS2 receptor
Gene Aliases: MmPEX7; PBD9B; PEX7; PTS2R; RCDP1; RD
UniProt ID: (Human) O00628, (Mouse) P97865
Entrez Gene ID: (Human) 5191, (Rat) 308718, (Mouse) 18634
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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