Methyllysine-binding protein, component of the MOF histone acetyltransferase protein complex. Not required for maintaining the global histone H4 'Lys-16' acetylation (H4K16ac) levels or locus specific histone acetylation, but instead works downstream in transcriptional regulation of MOF target genes. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. Contributes to methyllysine-dependent p53/TP53 stabilization and up-regulation after DNA damage.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Glioma-expressed antigen 2; Hepatocellular carcinoma-associated antigen 58; Hepatocellular carcinoma-associated antigen 58 homolog; Novel zinc finger protein; PHD finger protein 20; Transcription factor TZP; tudor domain containing 20A
Gene Aliases: 6820402O20Rik; C20orf104; GLEA2; HCA58; NZF; PHF20; TDRD20A; TZP