Phosphatidylinositolpolyphosphates (PtdInsPs) are centrally involved in many biologic processes, ranging from cell growth and organization of the actin cytoskeleton to endo- and exocytosis. PI4KII phosphorylates PtdIns at the D-4 position, an essential step in the biosynthesis of PtdInsPs (Barylko et al., 2001).
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Protein Aliases: 55 kDa type II phosphatidylinositol 4-kinase; null; phosphatidylinositol 4-kinase; Phosphatidylinositol 4-kinase type 2-alpha; phosphatidylinositol 4-kinase type II; phosphatidylinositol 4-kinase type II (PI4KII); Phosphatidylinositol 4-kinase type II-alpha
Gene Aliases: Pi4k2; PI4K2A; PI4KII; PIK42A
Molecular Function: kinase