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PIBF Antibody (BS-0420R) in IHC (P)
Paraformaldehyde-fixed, paraffin embedded Rat Testis; Antigen retrieval by boiling in sodium citrate buffer (pH6) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 30 minutes; Blocking buffer (BSA or normal goat serum) at 37°C for 20min; Antibody incubation with Rabbit Anti-PIBF Polyclonal Antibody, Unconjugated (bs-0420R ) at 1:500 overnight at 4°C, followed by a conjugated secondary and D... View More
Product Details
BS-0420R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human PIBF, amino acids 551-650.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Mediator of progesterone that by acting on the phospholipase A2 enzyme interferes with arachidonic acid metabolism, induces a Th2 biased immune response, and by controlling NK activity exerts an anti-abortive effect.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Centrosomal protein of 90 kDa; CEP90; PIBF; progesterone immunomodulatory binding factor 1; progesterone-induced blocking factor 1; Progesterone-induced-blocking factor 1; RP11-505F3.1
Gene Aliases: C13orf24; CEP90; PIBF; PIBF1; RGD1305077
UniProt ID: (Human) Q8WXW3
Entrez Gene ID: (Human) 10464, (Mouse) 52023, (Rat) 306104
biological_process
immune system process
mitotic metaphase plate congression
activation of JAK1 kinase activity
negative regulation of prostaglandin biosynthetic process
negative regulation of interleukin-12 production
positive regulation of interleukin-10 production
negative regulation of natural killer cell activation
nonmotile primary cilium assembly
negative regulation of tyrosine phosphorylation of Stat4 protein
positive regulation of tyrosine phosphorylation of Stat6 protein
protein localization to centrosome
mitotic spindle assembly
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