This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. View Details
Immunogen sequence: AECSRLLQIL ELGRHSECVH VTEEEQLQLR EILERRGSGE LYEHEKDLVW KLRHEVQEHF PEALARLLLV TKWN
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.
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Protein Aliases: Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta; Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform; phosphatidylinositol-4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform; phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta; phosphoinositide-3-kinase C; phosphoinositide-3-kinase, catalytic, delta polypeptide variant p37delta; PI3-kinase p110 subunit delta; PI3-kinase subunit delta; PI3K delta; PI3K-p110delta; pi3kcd; PI3Kdelta; PI3Kp110delta; PtdIns-3-kinase subunit p110-delta
Gene Aliases: APDS; IMD14; p110D; P110DELTA; PI3K; PIK3CD
UniProt ID: (Human) Q5SR49
Entrez Gene ID: (Human) 5293