Search
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
PIK3CD Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Product Details
PA5-86800
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to residues in Human PI3K p110delta.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Purity is > 95% by SDS-PAGE.
Target Information
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: catalytic phosphatidylinositol 3-kinase delta; p100 delta; phosphatidylinositol 3-kinase catalytic delta polypeptide; phosphatidylinositol 3-kinase catalytic subunit delta; phosphatidylinositol 3-kinase p110 delta; Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta; Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform; phosphatidylinositol-4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform; phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta; phosphoinositide 3 kinase P110delta; phosphoinositide-3-kinase C; phosphoinositide-3-kinase, catalytic, delta polypeptide; phosphoinositide-3-kinase, catalytic, delta polypeptide variant p37delta; PI3-kinase p110 subunit delta; PI3-kinase subunit delta; PI3K delta; PI3K-delta; PI3K-p110delta; pi3kcd; PI3Kdelta; PI3Kp110delta; ptdIns-3-kinase subunit delta; PtdIns-3-kinase subunit p110-delta
Gene Aliases: 2410099E07Rik; 2610208K16Rik; APDS; AW545373; IMD14; p110D; P110DELTA; PI3K; PIK3CD
UniProt ID: (Human) O00329, (Mouse) O35904
Entrez Gene ID: (Human) 5293, (Mouse) 18707, (Rat) 366508
protein binding
ATP binding
1-phosphatidylinositol-3-kinase activity
phosphatidylinositol 3-kinase activity
1-phosphatidylinositol-4-phosphate 3-kinase activity
phosphatidylinositol-4,5-bisphosphate 3-kinase activity
nucleotide binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
phosphotransferase activity, alcohol group as acceptor
kinase
natural killer cell differentiation
cytokine production
adaptive immune response
mast cell chemotaxis
respiratory burst involved in defense response
protein phosphorylation
phosphatidylinositol biosynthetic process
inflammatory response
signal transduction
positive regulation of gene expression
T cell chemotaxis
phosphatidylinositol 3-kinase signaling
regulation of phosphatidylinositol 3-kinase signaling
natural killer cell activation
T cell differentiation
positive regulation of cell migration
neutrophil chemotaxis
natural killer cell chemotaxis
B cell chemotaxis
phosphatidylinositol-3-phosphate biosynthetic process
T cell activation
B cell activation
mast cell degranulation
innate immune response
phosphatidylinositol phosphorylation
phosphatidylinositol-mediated signaling
T cell receptor signaling pathway
B cell receptor signaling pathway
mast cell differentiation
neutrophil extravasation
B cell homeostasis
immune system process
chemotaxis
cell surface receptor signaling pathway
phosphorylation
cell differentiation
platelet activation
homeostasis of number of cells
defense response to fungus
cell chemotaxis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support