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Invitrogen
PIK3CD Monoclonal Antibody (OTI2H3)
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PIK3CD Antibody (MA5-26514) in IHC (P)
Immunohistochemistry was performed on paraffin-embedded adenocarcinoma of human endometrium tissue. To expose target proteins, 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min was used. Following antigen retrieval, tissues were probed with a PIK3CD monoclonal antibody (Product # MA5-26514).
Product Details
MA5-26514
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
OTI2H3
Immunogen
Human recombinant protein fragment corresponding to amino acids 286-610 of PIK3CD produced in E.coli
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 1% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta; Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform; phosphatidylinositol-4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform; phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta; phosphoinositide-3-kinase C; phosphoinositide-3-kinase, catalytic, delta polypeptide variant p37delta; PI3-kinase p110 subunit delta; PI3-kinase subunit delta; PI3K delta; PI3K-p110delta; pi3kcd; PI3Kdelta; PI3Kp110delta; PtdIns-3-kinase subunit p110-delta
Gene Aliases: APDS; IMD14; p110D; P110DELTA; PI3K; PIK3CD
UniProt ID: (Human) O00329
Entrez Gene ID: (Human) 5293
natural killer cell differentiation
cytokine production
adaptive immune response
mast cell chemotaxis
respiratory burst involved in defense response
protein phosphorylation
phosphatidylinositol biosynthetic process
inflammatory response
signal transduction
positive regulation of gene expression
T cell chemotaxis
phosphatidylinositol 3-kinase signaling
regulation of phosphatidylinositol 3-kinase signaling
natural killer cell activation
T cell differentiation
positive regulation of cell migration
neutrophil chemotaxis
natural killer cell chemotaxis
B cell chemotaxis
phosphatidylinositol-3-phosphate biosynthetic process
T cell activation
B cell activation
mast cell degranulation
innate immune response
phosphatidylinositol phosphorylation
phosphatidylinositol-mediated signaling
T cell receptor signaling pathway
B cell receptor signaling pathway
mast cell differentiation
neutrophil extravasation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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