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Invitrogen
PIWIL1 Polyclonal Antibody
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Product Details
PA5-96072
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-160 of mouse PIWIL1 (NP_0672861)
Conjugate
Form
Liquid
Concentration
1.34 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive Samples: Mouse testis, Mouse liver, Rat testis; Cellular Location: Cytoplasm
Immunogen sequence: MTGRARARAR GRARGQETVQ HVGAAASQQP GYIPPRPQQS PTEGDLVGRG RQRGMVVGAT SKSQELQISA GFQELSLAER GGRRRDFHDL GVNTRQNLDH VKESKTGSSG IIVKLSTNHF RLTSRPQWAL YQYHIDYNPL MEARRLRSAL LFQHEDLIGR
Target Information
Hiwi is a member of the Piwi /Argonaute protein family. Hiwi is specifically expressed in germline cells such as spermatocytes and round spermatids during spermatogenesis. Hiwi is also expressed in CD34+ hematopoietic progenitors, but not in CD34- hematopoietic cells, suggesting a role for this gene in the maintenance of hematopoietic stem cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CT80; HILI; member of the PIWI family; mili; Miwi like; Miwi likw; piwi homolog; piwi like homolog 1; piwi-like 1; piwi-like homolog 1; Piwi-like protein 1; piwi-like protein 2; PIWIL1L; piwil2-like protein; unnamed protein product
Gene Aliases: CT80.1; HIWI; MIWI; PIWI; PIWIL1
UniProt ID: (Human) Q96J94, (Mouse) Q9JMB7
Entrez Gene ID: (Human) 9271, (Rat) 363912, (Mouse) 57749
regulation of translation
spermatogenesis
spermatid development
cell differentiation
gene silencing by RNA
piRNA metabolic process
sperm chromatin condensation
meiotic cell cycle
primary piRNA processing
piRNA-mediated gene silencing by mRNA destabilization
transposable element silencing by piRNA-mediated heterochromatin formation
pachytene
multicellular organism development
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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