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Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
1 µg/mL | - |
Product Specifications | |
---|---|
Species Reactivity |
Human, Mouse, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
An 18 amino acid peptide near the amino terminus of human PIWI-L3. |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
1 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS |
Contains |
0.02% sodium azide |
Storage conditions |
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C |
RRID |
AB_11151964 |
A suggested positive control is NIH-3T3 cell lysate.
PA5-21052 can be used with blocking peptide PEP-1166.
PIWI-L3 is a member of the PIWI subfamily of Argonaute proteins, evolutionarily conserved proteins containing both PAZ and Piwi motifs that are crucial for the biogenesis and function of small non-coding RNAs and play important roles in stem cell self-renewal, RNA silencing, and translational regulation in diverse organisms. Recent studies have shown that overexpression of PIWI-L3 (as well as other PIWI-like proteins) are potential biomarkers for astrocytic glioma, meningioma, and other cancers.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: piwi-like 3; Piwi-like protein 3; piwi-like RNA-mediated gene silencing 3
Gene Aliases: HIWI3; PIWIL3
UniProt ID: (Human) Q7Z3Z3
Entrez Gene ID: (Human) 440822
Molecular Function:
translation initiation factor
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