FIGURE: 1 / 2
A suggested positive control is NIH-3T3 cell lysate.
PA5-21052 can be used with blocking peptide PEP-1166.
PIWI-L3 is a member of the PIWI subfamily of Argonaute proteins, evolutionarily conserved proteins containing both PAZ and Piwi motifs that are crucial for the biogenesis and function of small non-coding RNAs and play important roles in stem cell self-renewal, RNA silencing, and translational regulation in diverse organisms. Recent studies have shown that overexpression of PIWI-L3 (as well as other PIWI-like proteins) are potential biomarkers for astrocytic glioma, meningioma, and other cancers.
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Protein Aliases: piwi-like 3; Piwi-like protein 3; piwi-like RNA-mediated gene silencing 3
Gene Aliases: HIWI3; PIWIL3
UniProt ID: (Human) Q7Z3Z3
Entrez Gene ID: (Human) 440822
Molecular Function: translation initiation factor