This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. View Details
Immunogen sequence: LRYLVSRSKQ PLDFMEGNQN TPRFMWLKTV FEAADVDGNG IMLEDTSVEL IKQLNPTLKE AKIRLKFKEI QKSKEKLTTR VTEEEF
Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 99%.
Involved in an inositol phospholipid-based intracellular signaling cascade. Shows no PLC activity to phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol. Component in the phospho-dependent endocytosis process of GABA A receptor. Regulates the turnover of receptors and thus contributes to the maintenance of GABA-mediated synaptic inhibition. Its aberrant expression could contribute to the genesis and progression of lung carcinoma. Acts as a inhibitor of PPP1C.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Inactive phospholipase C-like protein 1; phospholipase C related, but catalytically inactive protein; phospholipase C, epsilon; Phospholipase C-deleted in lung carcinoma; phospholipase C-like 1; Phospholipase C-related but catalytically inactive protein; PLC-L1; PLCL1; PRIP; protein phosphatase 1, regulatory subunit 127
Gene Aliases: PLCE; PLCL; PLCL1; PLDL1; PPP1R127; PRIP
UniProt ID: (Human) Q15111
Entrez Gene ID: (Human) 5334