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Invitrogen
PLK2 Polyclonal Antibody
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FIGURE: 1 / 2
PLK2 Antibody (PA5-101863) in IHC (P)
Immunohistochemistry analysis of PLK2 in rat heart tissue. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with PLK2 polyclonal antibody (Product # PA5-101863) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
Product Details
PA5-101863
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human PLK2(Accession Q9NYY3), corresponding to amino acid residues E294-S344.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total PLK2.
Target Information
PLK2 is a serum inducible serine/threonine kinase that is a member of the polo family of serine/threonine kinases which have a role in normal cell division. The kinase may play a role in embryogenesis, wound healing, and neoplasia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: h PLK-2; hSNK; PLK-2; polo-like kinase 1; Polo-like kinase 2; Serine/threonine-protein kinase PLK2; Serine/threonine-protein kinase SNK; Serum-inducible kinase
Gene Aliases: hPlk2; hSNK; PLK2; SNK
UniProt ID: (Human) Q9NYY3, (Mouse) P53351, (Rat) Q9R012
Entrez Gene ID: (Human) 10769, (Mouse) 20620, (Rat) 83722
protein serine/threonine kinase activity
signal transducer activity
protein binding
ATP binding
protein complex binding
ATP-dependent protein binding
nucleotide binding
protein kinase activity
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
non-receptor serine/threonine protein kinase
protein modifying enzyme
G1/S transition of mitotic cell cycle
protein phosphorylation
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
mitotic spindle organization
mitotic cell cycle checkpoint
Ras protein signal transduction
memory
positive regulation of autophagy
peptidyl-serine phosphorylation
positive regulation of protein binding
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
Rap protein signal transduction
negative regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of protein catabolic process
regulation of centriole replication
regulation of synaptic plasticity
long-term synaptic potentiation
long term synaptic depression
negative regulation of dendritic spine development
mitotic cell cycle
phosphorylation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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