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Proteintech
PLK3 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
10977-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PLK3 Fusion Protein Ag1431 (298-646 aa encoded by BC013899)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.33 mg/mL
Amount
49.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: SPRDRPSID QILRHDFFTK GYTPDRLPIS SCVTVPDLTP PNPARSLFAK VTKSLFGRKK KSKNHAQERD EVSGLVSGLM RTSVGHQDAR PEAPAASGPA PVSLVETAPE DSSPRGTLAS SGDGFEEGLT VATVVESALC ALRNCIAFMP PAEQNPAPLA QPEPLVWVSK WVDYSNKFGF GYQLSSRRVA VLFNNGTHMA LSANRKTVHY NPTSTKHFSF SVGAVPRALQ PQLGILRYFA SYMEQHLMKG GDLPSVEEVE VPAPPLLLQW VKTDQALLML FSDGTVQVNF YGDHTKLILS GWEPLLVTFV ARNRSACTYL ASHLRQLGCS PDLRQRLRYA LRLLRDRSPA (298-646 aa encoded by BC013899)
Target Information
PLK3 is a member of the polo family of serine/threonine kinases. PLK3 is involved in the regulation of M phase in the cell cycle. CNK contains both a catalytic domain and a putative regulatory domain. It may play a role in regulation of cell cycle progression and tumorigenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: cytokine inducible kinase; cytokine-inducible serine/threonine-protein kinase; FGF-inducible kinase; PLK-3; proliferation-related kinase; putative serine/threonine kinase; serine-threonine kinase; unnamed protein product
Gene Aliases: CNK; FNK; PLK-3; PRK
UniProt ID: (Human) Q9H4B4, (Rat) Q9R011
Entrez Gene ID: (Human) 1263, (Mouse) 12795, (Rat) 58936
G1/S transition of mitotic cell cycle
negative regulation of transcription from RNA polymerase II promoter
response to reactive oxygen species
response to osmotic stress
cellular response to DNA damage stimulus
mitotic spindle organization
response to radiation
regulation of cell communication
regulation of signaling
cytoplasmic microtubule organization
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
regulation of cytokinesis
negative regulation of apoptotic process
mitotic G1/S transition checkpoint
regulation of cell division
negative regulation of protein kinase B signaling
Golgi disassembly
positive regulation of intracellular protein transport
positive regulation of chaperone-mediated autophagy
regulation of G1/S transition of mitotic cell cycle
protein phosphorylation
regulation of synaptic plasticity
regulation of long-term neuronal synaptic plasticity
G2/M transition of mitotic cell cycle
apoptotic process
endomitotic cell cycle
positive regulation of autophagy
regulation of cell cycle process
DNA damage response, signal transduction by p53 class mediator
positive regulation of protein catabolic process
regulation of signal transduction by p53 class mediator
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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