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Invitrogen
PLP1 Polyclonal Antibody
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Product Details
PA3-151
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to the C-terminal residues K(269) L M G R G T K(276) of PLP.
Conjugate
Form
Liquid
Concentration
Conc. Not Determined
Storage buffer
whole serum
Contains
0.05% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
PA3-151 detects proteolipid protein in mouse samples.
PA3-151 has been used successfully in Western blot and immunocytochemistry procedures. By Western blot this antibody detects a ~23-26 kDa proteins representing the proteolipid protein and the splice variant DM20 in adult mouse brain samples.
The PA3-151 immunogen is a synthetic peptide corresponding to the C-terminal residues K(269) L M G R G T K(276) of PLP.
Target Information
PLP1 is a transmembrane proteolipid protein that is the predominant myelin protein present in the central nervous system. It may play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in this gene cause X-linked Pelizaeus-Merzbacher disease and spastic paraplegia type 2. Alternatively spliced transcript variants encoding distinct isoforms or having different 5' UTRs, have been identified for this gene.This gene encodes a transmembrane proteolipid protein that is the predominant myelin protein present in the central nervous system. It may play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in this gene cause X-linked Pelizaeus-Merzbacher disease and spastic paraplegia type 2. Alternatively spliced transcript variants encoding distinct isoforms or having different 5' UTRs, have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Lipophilin; Myelin proteolipid protein; myelin synthesis deficiency; PLP; proteolipid; rump shaker
Gene Aliases: DM20; jimpy; jp; msd; Plp; Plp1; rsh
UniProt ID: (Mouse) P60202
Entrez Gene ID: (Mouse) 18823
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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