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Invitrogen
PLUNC Polyclonal Antibody
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FIGURE: 1 / 1
PLUNC Antibody (PA5-117146) in WB
Western blot analysis of PLUNC in extracts of various cell lines. Samples were incubated with PLUNC Polyclonal antibody (Product # PA5-117146) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.
Product Details
PA5-117146
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 20-256 of human BPIFA1 (NP_0576671)
Conjugate
Form
Liquid
Concentration
1.73 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive Samples: Mouse liver, Rat heart
Immunogen sequence: QFGGLPVPLD QTLPLNVNPA LPLSPTGLAG SLTNALSNGL LSGGLLGILE NLPLLDILKP GGGTSGGLLG GLLGKVTSVI PGLNNIIDIK VTDPQLLELG LVQSPDGHRL YVTIPLGIKL QVNTPLVGAS LLRLAVKLDI TAEILAVRDK QERIHLVLGD CTHSPGSLQI SLLDGLGPLP IQGLLDSLTG ILNKVLPELV QGNVCPLVNE VLRGLDITLV HDIVNMLIHG LQFVIKV
Target Information
PLUNC is the human homolog of murine plunc and is specifically expressed in the upper airways and nasopharyngeal regions. The exact biological function of this protein is not known, however, it has been suggested to be involved in inflammatory responses to irritants in the upper airways. It may also serve as a potential molecular marker for detection of micrometastasis in non-small-cell lung cancer. This gene is the human homolog of murine plunc, and like the mouse gene, is specifically expressed in the upper airways and nasopharyngeal regions. The exact biological function of this gene is not known, however, it has been suggested to be involved in inflammatory responses to irritants in the upper airways. It may also serve as a potential molecular marker for detection of micrometastasis in non-small-cell lung cancer. Multiple transcript variants resulting from alternative splicing in the 3' UTR have been detected, but the full-length nature of only two is known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: BPI fold-containing family A member 1; ES cell-related protein; LPLUNC3; LUNXNASG; Palate lung and nasal epithelium clone protein; palate, lung and nasal epithelium associated; palate, lung, and nasal epithelium associated; palate, lung, and nasal epithelium carcinoma associated protein; palate, lung, and nasal epithelium clone; palate, lung, and nasal epithelium expressed transcript; protein Plunc; short palate; SPLUNC1SPURT
Gene Aliases: Bpifa1; LUNX; NASG; Plunc; SPLUNC1; SPURT
UniProt ID: (Rat) Q8K4I4, (Mouse) P97361
Entrez Gene ID: (Rat) 246238, (Mouse) 18843
antibacterial humoral response
innate immune response
regulation of liquid surface tension
multicellular organismal water homeostasis
negative regulation of single-species biofilm formation in or on host organism
regulation of sodium ion transmembrane transport
immune system process
defense response to bacterium
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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