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Product Details
23795-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Not Applicable
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PLXNB1 Fusion Protein Ag20719 (20-369 aa encoded by BC146793)
Conjugate
Form
Liquid
Concentration
0.23 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: LQPLPPTAF TPNGTYLQHL ARDPTSGTLY LGATNFLFQL SPGLQLEATV STGPVLDSRD CLPPVMPDEC PQAQPTNNPN QLLLVSPGAL VVCGSVHQGV CEQRRLGQLE QLLLRPERPG DTQYVAANDP AVSTVGLVAQ GLAGEPLLFV GRGYTSRGVG GGIPPITTRA LWPPDPQAAF SYEETAKLAV GRLSEYSHHF VSAFARGASA YFLFLRRDLQ AQSRAFRAYV SRVCLRDQHY YSYVELPLAC EGGRYGLIQA AAVATSREVA HGEVLFAAFS SAAPPTVGRP PSAAAGASGA SALCAFPLDE VDRLANRTRD ACYTREGRAE DGTEVAYIEY DVNSDCAQLP V (20-369 aa encoded by BC146793)
Target Information
Plexin B1 is a protein of the plexin family that in humans is encoded by the PLXNB1gene. Receptor for SEMA4D. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: plexin 1; plexin 5; plexin-A1; Plexin-B1; Semaphorin receptor SEP
Gene Aliases: 2900002G15Rik; AU042020; KIAA0407; mKIAA0407; PLEXIN-B1; PLXN5; PLXNB1; SEP
UniProt ID: (Human) O43157, (Mouse) Q8CJH3
Entrez Gene ID: (Human) 5364, (Mouse) 235611
negative regulation of cell adhesion
signal transduction
regulation of cell shape
positive regulation of phosphatidylinositol 3-kinase signaling
cell migration
regulation of cell migration
negative regulation of osteoblast proliferation
intracellular signal transduction
regulation of GTPase activity
positive regulation of GTPase activity
ossification involved in bone maturation
axon extension
neuron projection morphogenesis
positive regulation of axonogenesis
regulation of cytoskeleton organization
semaphorin-plexin signaling pathway
semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis
semaphorin-plexin signaling pathway involved in axon guidance
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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