Search
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
PLXNB1 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Product Details
PA5-59211
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human PLXNB1. Recombinant protein control fragment (Product #RP-96424).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: PGDNECVMEL EGLEVVVEAR VECEPPPDTQ CHVTCQQHQL SYEALQPELR VGLFLRRAGR LRVDSAEGLH VVLYDCSVGH GDCSRCQTAM PQYGCVWC
Highest antigen sequence identity to the following orthologs: Mouse - 79%, Rat - 82%.
Target Information
Plexin B1 is a protein of the plexin family that in humans is encoded by the PLXNB1gene. Receptor for SEMA4D. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: plexin 1; plexin 5; plexin-A1; Plexin-B1; Semaphorin receptor SEP
Gene Aliases: KIAA0407; PLEXIN-B1; PLXN5; PLXNB1; SEP
UniProt ID: (Human) O43157
Entrez Gene ID: (Human) 5364
negative regulation of cell adhesion
signal transduction
regulation of cell shape
positive regulation of phosphatidylinositol 3-kinase signaling
cell migration
regulation of cell migration
negative regulation of osteoblast proliferation
intracellular signal transduction
regulation of GTPase activity
positive regulation of GTPase activity
ossification involved in bone maturation
axon extension
neuron projection morphogenesis
positive regulation of axonogenesis
regulation of cytoskeleton organization
semaphorin-plexin signaling pathway
semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis
semaphorin-plexin signaling pathway involved in axon guidance
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support