Immunogen sequence: HYTLDFLSPK TFQQILEYAY TATLQAKAED LDDLLYAAEI LEIEYLEEQC LKMLETIQAS DDNDTEATMA DGGAEEEEDR KARYLKNIFI SKHSSEESGY ASVAGQSLPG PMVDQSPSVS TSFGLSA
PLZF is a member of the Krueppel C2H2-type zinc-finger protein family and a zinc finger transcription factor that contains nine Kruppel-type zinc finger domains at the carboxyl terminus. This protein is located in the nucleus, is involved in cell cycle progression, and interacts with a histone deacetylase. Specific instances of aberrant gene rearrangement at this locus have been associated with acute promyelocytic leukemia (APL).
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Protein Aliases: PLZF; promyelocytic leukaemia zinc finger; Promyelocytic leukemia zinc finger protein; Zinc finger and BTB domain-containing protein 16; Zinc finger protein 145; zinc finger protein 145 (Kruppel-like, expressed in promyelocytic leukemia); Zinc finger protein PLZF; ZNF145
Gene Aliases: PLZF; ZBTB16; ZNF145
UniProt ID: (Human) Q05516
Entrez Gene ID: (Human) 7704