Product References
A mitochondrial iron-responsive pathway regulated by DELE1.
Molecular cell
Sekine Y,Houston R,Eckl EM,Fessler E,Narendra DP,Jae LT,Sekine S
Thu Jun 15 00:00:00 EDT 2023
Mutant CHCHD10 causes an extensive metabolic rewiring that precedes OXPHOS dysfunction in a murine model of mitochondrial cardiomyopathy.
Cell reports
Sayles NM,Southwell N,McAvoy K,Kim K,Pesini A,Anderson CJ,Quinzii C,Cloonan S,Kawamata H,Manfredi G
Tue Mar 08 00:00:00 EST 2022
In Situ Peroxidase Labeling Followed by Mass-Spectrometry Reveals TIA1 Interactome.
Biology
Gourdomichali O,Zonke K,Kattan FG,Makridakis M,Kontostathi G,Vlahou A,Doxakis E
Fri Feb 11 00:00:00 EST 2022
DELE1 tracks perturbed protein import and processing in human mitochondria.
Nature communications
Fessler E,Krumwiede L,Jae LT
Wed Apr 06 00:00:00 EDT 2022
The role of SQSTM1 (p62) in mitochondrial function and clearance in human cortical neurons.
Stem cell reports
Poon A,Saini H,Sethi S,O'Sullivan GA,Plun-Favreau H,Wray S,Dawson LA,McCarthy JM
Tue May 11 00:00:00 EDT 2021
Mitochondrial Aurora kinase A induces mitophagy by interacting with MAP1LC3 and Prohibitin 2.
Life science alliance
Bertolin G,Alves-Guerra MC,Cheron A,Burel A,Prigent C,Le Borgne R,Tramier M
Tue Jun 01 00:00:00 EDT 2021
Quantitative dSTORM super-resolution microscopy localizes Aurora kinase A/AURKA in the mitochondrial matrix.
Biology of the cell
Durel B,Kervrann C,Bertolin G
Mon Nov 01 00:00:00 EDT 2021
TP53INP1 exerts neuroprotection under ageing and Parkinson's disease-related stress condition.
Cell death & disease
Dinh E,Rival T,Carrier A,Asfogo N,Corti O,Melon C,Salin P,Lortet S,Kerkerian-Le Goff L
Sat May 08 00:00:00 EDT 2021
Revealing molecular pathways for cancer cell fitness through a genetic screen of the cancer translatome.
Cell reports
Kuzuoglu-Ozturk D,Hu Z,Rama M,Devericks E,Weiss J,Chiang GG,Worland ST,Brenner SE,Goodarzi H,Gilbert LA,Ruggero D
Tue Jun 29 00:00:00 EDT 2021
Mitochondrial stress is relayed to the cytosol by an OMA1-DELE1-HRI pathway.
Nature
Guo X,Aviles G,Liu Y,Tian R,Unger BA,Lin YT,Wiita AP,Xu K,Correia MA,Kampmann M
Sun Mar 01 00:00:00 EST 2020
LRRK2 impairs PINK1/Parkin-dependent mitophagy via its kinase activity: pathologic insights into Parkinson's disease.
Human molecular genetics
Bonello F,Hassoun SM,Mouton-Liger F,Shin YS,Muscat A,Tesson C,Lesage S,Beart PM,Brice A,Krupp J,Corvol JC,Corti O
Wed May 15 00:00:00 EDT 2019
LRRK2 impairs PINK1/Parkin-dependent mitophagy via its kinase activity: pathologic insights into Parkinson's disease.
Human molecular genetics
Bonello F,Hassoun SM,Mouton-Liger F,Shin YS,Muscat A,Tesson C,Lesage S,Beart PM,Brice A,Krupp J,Corvol JC,Corti O
Wed May 15 00:00:00 EDT 2019
PARL partitions the lipid transfer protein STARD7 between the cytosol and mitochondria.
The EMBO journal
Saita S,Tatsuta T,Lampe PA,König T,Ohba Y,Langer T
Thu Feb 15 00:00:00 EST 2018
Sam50 Regulates PINK1-Parkin-Mediated Mitophagy by Controlling PINK1 Stability and Mitochondrial Morphology.
Cell reports
Jian F,Chen D,Chen L,Yan C,Lu B,Zhu Y,Chen S,Shi A,Chan DC,Song Z
Tue Jun 05 00:00:00 EDT 2018
Sam50 Regulates PINK1-Parkin-Mediated Mitophagy by Controlling PINK1 Stability and Mitochondrial Morphology.
Cell reports
Jian F,Chen D,Chen L,Yan C,Lu B,Zhu Y,Chen S,Shi A,Chan DC,Song Z
Tue Jun 05 00:00:00 EDT 2018
AKT signalling selectively regulates PINK1 mitophagy in SHSY5Y cells and human iPSC-derived neurons.
Scientific reports
Soutar MPM,Kempthorne L,Miyakawa S,Annuario E,Melandri D,Harley J,O'Sullivan GA,Wray S,Hancock DC,Cookson MR,Downward J,Carlton M,Plun-Favreau H
Mon Jun 11 00:00:00 EDT 2018
AKT signalling selectively regulates PINK1 mitophagy in SHSY5Y cells and human iPSC-derived neurons.
Scientific reports
Soutar MPM,Kempthorne L,Miyakawa S,Annuario E,Melandri D,Harley J,O'Sullivan GA,Wray S,Hancock DC,Cookson MR,Downward J,Carlton M,Plun-Favreau H
Mon Jun 11 00:00:00 EDT 2018
Aurora kinase A localises to mitochondria to control organelle dynamics and energy production.
eLife
Bertolin G,Bulteau AL,Alves-Guerra MC,Burel A,Lavault MT,Gavard O,Le Bras S,Gagné JP,Poirier GG,Le Borgne R,Prigent C,Tramier M
Thu Aug 02 00:00:00 EDT 2018
Aurora kinase A localises to mitochondria to control organelle dynamics and energy production.
eLife
Bertolin G,Bulteau AL,Alves-Guerra MC,Burel A,Lavault MT,Gavard O,Le Bras S,Gagné JP,Poirier GG,Le Borgne R,Prigent C,Tramier M
Thu Aug 02 00:00:00 EDT 2018
Aurora kinase A localises to mitochondria to control organelle dynamics and energy production.
eLife
Bertolin G,Bulteau AL,Alves-Guerra MC,Burel A,Lavault MT,Gavard O,Le Bras S,Gagné JP,Poirier GG,Le Borgne R,Prigent C,Tramier M
Thu Aug 02 00:00:00 EDT 2018
Aurora kinase A localises to mitochondria to control organelle dynamics and energy production.
eLife
Bertolin G,Bulteau AL,Alves-Guerra MC,Burel A,Lavault MT,Gavard O,Le Bras S,Gagné JP,Poirier GG,Le Borgne R,Prigent C,Tramier M
Thu Aug 02 00:00:00 EDT 2018
LONP1 Is Required for Maturation of a Subset of Mitochondrial Proteins, and Its Loss Elicits an Integrated Stress Response.
Molecular and cellular biology
Zurita Rendón O,Shoubridge EA
Mon Oct 15 00:00:00 EDT 2018
PARL mediates Smac proteolytic maturation in mitochondria to promote apoptosis.
Nature cell biology
Saita S,Nolte H,Fiedler KU,Kashkar H,Venne AS,Zahedi RP,Krüger M,Langer T
Sat Apr 01 00:00:00 EDT 2017
PARL mediates Smac proteolytic maturation in mitochondria to promote apoptosis.
Nature cell biology
Saita S,Nolte H,Fiedler KU,Kashkar H,Venne AS,Zahedi RP,Krüger M,Langer T
Sat Apr 01 00:00:00 EDT 2017
Embryonic cardiomyocytes can orchestrate various cell protective mechanisms to survive mitochondrial stress.
Journal of molecular and cellular cardiology
Magarin M,Pohl T,Lill A,Schulz H,Blaschke F,Heuser A,Thierfelder L,Donath S,Drenckhahn JD
Mon Aug 01 00:00:00 EDT 2016
Embryonic cardiomyocytes can orchestrate various cell protective mechanisms to survive mitochondrial stress.
Journal of molecular and cellular cardiology
Magarin M,Pohl T,Lill A,Schulz H,Blaschke F,Heuser A,Thierfelder L,Donath S,Drenckhahn JD
Mon Aug 01 00:00:00 EDT 2016
The endoplasmic reticulum-mitochondria interface is perturbed in PARK2 knockout mice and patients with PARK2 mutations.
Human molecular genetics
Gautier CA,Erpapazoglou Z,Mouton-Liger F,Muriel MP,Cormier F,Bigou S,Duffaure S,Girard M,Foret B,Iannielli A,Broccoli V,Dalle C,Bohl D,Michel PP,Corvol JC,Brice A,Corti O
Fri Jul 15 00:00:00 EDT 2016
The endoplasmic reticulum-mitochondria interface is perturbed in PARK2 knockout mice and patients with PARK2 mutations.
Human molecular genetics
Gautier CA,Erpapazoglou Z,Mouton-Liger F,Muriel MP,Cormier F,Bigou S,Duffaure S,Girard M,Foret B,Iannielli A,Broccoli V,Dalle C,Bohl D,Michel PP,Corvol JC,Brice A,Corti O
Fri Jul 15 00:00:00 EDT 2016
The TOMM machinery is a molecular switch in PINK1 and PARK2/PARKIN-dependent mitochondrial clearance.
Autophagy
Bertolin G,Ferrando-Miguel R,Jacoupy M,Traver S,Grenier K,Greene AW,Dauphin A,Waharte F,Bayot A,Salamero J,Lombès A,Bulteau AL,Fon EA,Brice A,Corti O
Fri Nov 01 00:00:00 EDT 2013
The TOMM machinery is a molecular switch in PINK1 and PARK2/PARKIN-dependent mitochondrial clearance.
Autophagy
Bertolin G,Ferrando-Miguel R,Jacoupy M,Traver S,Grenier K,Greene AW,Dauphin A,Waharte F,Bayot A,Salamero J,Lombès A,Bulteau AL,Fon EA,Brice A,Corti O
Fri Nov 01 00:00:00 EDT 2013
Mitochondrial processing peptidase regulates PINK1 processing, import and Parkin recruitment.
EMBO reports
Greene AW,Grenier K,Aguileta MA,Muise S,Farazifard R,Haque ME,McBride HM,Park DS,Fon EA
Sun Apr 01 00:00:00 EDT 2012
Mitochondrial processing peptidase regulates PINK1 processing, import and Parkin recruitment.
EMBO reports
Greene AW,Grenier K,Aguileta MA,Muise S,Farazifard R,Haque ME,McBride HM,Park DS,Fon EA
Sun Apr 01 00:00:00 EDT 2012
