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NeoBiotechnologies
PMS2 (Postmeiotic Segregation Increased 2) Recombinant Rabbit Monoclonal Antibody (PMS2, 4373R)
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FIGURE: 1 / 4
PMS2 (Postmeiotic Segregation Increased 2) Antibody (5395-RBM1-P1) in IHC (P)
Immunohistochemistry (Paraffin) analysis performed in formalin fixed, paraffin-embedded human colon carcinoma using PMS2 (Postmeiotic Segregation Increased 2) Recombinant Monoclonal Antibody (Product # 5395-RBM1-P1).
Product Details
5395-RBM1-P1
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
PMS2, 4373R
Immunogen
A synthetic peptide corresponding to residues within aa1-100 of human PMS2
Conjugate
Form
Liquid
Concentration
200 µg/mL
Purification
Protein A/G
Storage buffer
PBS, pH 7.4, with 0.05% BSA
Contains
0.05% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Immunohistochemistry (PFA fixed): incubate antibody for 30 min RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 degrees C followed by cooling at RT for 20 minutes.
Target Information
PMS1 protein homologue 2 (PMS2) is a DNA mismatch repair protein. Defects in PMS2 are a cause of hereditary non-polyposis cancer (HNPCC). Human PMS2 is an amino acid protein of 862 amino acids.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DNA mismatch repair protein PMS2; H_DJ0042M02.9; Mismatch repair endonuclease PMS2; PMS1 homolog 2, mismatch repair protein; PMS1 protein homolog 2; PMS2 postmeiotic segregation increased 2; similar to S. cerevisiae PMS1 Swiss-Prot Accession Number P14242, S. cerevisiae MLH1 GenBank Accession Number U07187, E. coli MUTL Swiss-Prot Accession Number P23367, Salmonella typhimurium MUTL Swiss-Prot Accession Number P14161, Streptococcus pneumoniae ; unnamed protein product
Gene Aliases: HNPCC4; LYNCH4; MLH4; MMRCS4; PMS-2; PMS2; PMS2CL; PMSL2
UniProt ID: (Human) P54278
Entrez Gene ID: (Human) 5395
DNA repair
mismatch repair
cellular response to DNA damage stimulus
response to xenobiotic stimulus
somatic hypermutation of immunoglobulin genes
somatic recombination of immunoglobulin gene segments
positive regulation of isotype switching to IgA isotypes
positive regulation of isotype switching to IgG isotypes
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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