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Abnova
PODN Polyclonal Antibody, MaxPab™
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Product Details
H00127435-B01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PODN (AAH30608, 1 a.a. approximately 661 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MEGARARGAQ LRLGERVRPV GRRSAPGRSR FHQPWRPGAS DSAPPAGTMA QSRVLLLLLL LPPQLHLGPV LAVRAPGFGR SGGHSLSPEE NEFAEEEPVL VLSPEEPGPG PAAVSCPRDC ACSQEGVVDC GGIDLREFPG DLPEHTNHLS LQNNQLEKIY PEELSRLHRL ETLNLQNNRL TSRGLPEKAF EHLTNLNYLY LANNKLTLAP RFLPNALISV DFAANYLTKI YGLTFGQKPN LRSVYLHNNK LADAGLPDNM FNGSSNVEVL ILSSNFLRHV PKHLPPALYK LHLKNNKLEK IPPGAFSELS SLRELYLQNN YLTDEGLDNE TFWKLSSLEY LDLSSNNLSR VPAGLPRSLV LLHLEKNAIR SVDANVLTPI RSLEYLLLHS NQLREQGIHP LAFQGLKRLH TVHLYNNALE RVPSGLPRRV RTLMILHNQI TGIGREDFAT TYFLEELNLS YNRITSPQVH RDAFRKLRLL RSLDLSGNRL HTLPPGLPRN VHVLKVKRNE LAALARGALA GMAQLRELYL TSNRLRSRAL GPRAWVDLAH LQLLDIAGNQ LTEIPEGLPE SLEYLYLQNN KISAVPANAF DSTPNLKGIF LRFNKLAVGS VVDSAFRRLK HLQVLDIEGN LEFGDISKDR GRLGKEKEEE EEEEEEEEET R
Target Information
Non-collagenous proteins of the small leucine-rich repeat (SLR) protein family are considered important components of the extracellular matrix. The extracellular matrix plays an integral role in the pivotal processes of development, tissue repair and metastasis by regulating cell proliferation, differentiation, adhesion and migration. Podocan, also known as PCAN, SLRR5A or PODN, is a 613 amino acid secreted protein belonging to the small leucine-rich proteoglycan (SLRP) family and the class V subfamily. Expressed in kidney, heart, liver, pancreas and vascular smooth muscle cells, Podocan exists as three alternatively spliced isoforms containing twenty LRR (leucine-rich repeats), a unique N-terminal cysteine-rich cluster pattern and a highly acidic C-terminal domain. Podocan is considered a glycoprotein containing N-linked oligosaccharides that may be involved in growth regulation in cardiovascular tissues. Encoded by a gene located on human chromosome 1, Podocan interacts type I collagen (COL1).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Podocan; podocan proteoglycan; PRO332; UNQ293
Gene Aliases: PCAN; PODN; SLRR5A; UNQ293/PRO332
UniProt ID: (Human) Q7Z5L7
Entrez Gene ID: (Human) 127435
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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