Immunogen sequence: IAKVSIGRLR PHFLSVCNPD FSQINCSEGY IQNYRCRGDD SKVQEARKSF
Phosphatidic acid phosphatase type 2 (PAP2) was originally identified as a plasma membrane enzyme that catalyses the dephosphorylation of the putative second messenger, phosphatidic acid (PA) to diacylglycerol (DG). Subsequently, multiple isoforms of PAP2 were cloned [2-5]. It was found that these enzymes dephosphorylate a number of lipid phosphates in vitro other than PA, including the potent bioactive lipids, lysophosphatidic acid (LPA) and sphingosine 1-phosphate (S1P). Therefore, they have been renamed lipid phosphate phosphatases (LPPs). Currently, there are four members of this family called LPP1, LPP1a, LPP2 and LPP3.
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Protein Aliases: Lipid phosphate phosphohydrolase 3; LPP3; PAP-2b; PAP2 beta; PAP2-beta; Phosphatidate phosphohydrolase type 2b; Phosphatidic acid phosphatase 2b; phosphatidic acid phosphatase type 2B; Phospholipid phosphatase 3; PPAP2B; type-2 phosphatidic acid phosphatase-beta; vascular endothelial growth factor and type I collagen inducible; Vascular endothelial growth factor and type I collagen-inducible protein; VCIP
Gene Aliases: Dri42; LPP3; PAP2B; PLPP3; PPAP2B; VCIP
UniProt ID: (Human) O14495
Entrez Gene ID: (Human) 8613