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Proteintech
PPAT Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
15401-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PPAT Fusion Protein Ag7618 (178-517 aa encoded by BC004200)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.33 mg/mL
Amount
49.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: KEAPTAYSL LIMHRDVIYA VRDPYGNRPL CIGRLIPVSD INDKEKKTSE TEGWVVSSES CSFLSIGARY YREVLPGEIV EISRHNVQTL DIISRSEGNP VAFCIFEYVY FARPDSMFED QMVYTVRYRC GQQLAIEAPV DADLVSTVPE SATPAALAYA GKCGLPYVEV LCKNRYVGRT FIQPNMRLRQ LGVAKKFGVL SDNFKGKRIV LVDDSIVRGN TISPIIKLLK ESGAKEVHIR VASPPIKYPC FMGINIPTKE ELIANKPEFD HLAEYLGANS VVYLSVEGLV SSVQEGIKFK KQKEKKHDIM IQENGNGLEC FEKSGHCTAC LTGKYPVELE W (178-517 aa encoded by BC004200)
Target Information
The protein encoded by this gene is a member of the purine/pyrimidine phosphoribosyltransferase family. This protein is a regulatory allosteric enzyme that catalyzes the first step of de novo purine nucleotide biosynthesis. This gene and PAICS/AIRC, a bifunctional enzyme catalyzing steps six and seven in the purine nucleotide biosynthesis pathway, are located in close proximity on chromosome 4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: ATase; EC 2.4.2.14; glutamine phosphoribosylpyrophosphatate amidotransferase; glutamine phosphoribosylpyrophosphate amidotransferase; glutamine PRPP amidotransferase; GPAT; unnamed protein product
Gene Aliases: 5730454C12Rik; ATASE; GPAT; PRAT
UniProt ID: (Human) Q06203, (Mouse) Q8CIH9, (Rat) P35433
Entrez Gene ID: (Human) 5471, (Mouse) 231327, (Rat) 117544
purine nucleotide biosynthetic process
GMP biosynthetic process
'de novo' IMP biosynthetic process
purine nucleobase biosynthetic process
'de novo' AMP biosynthetic process
'de novo' XMP biosynthetic process
glutamine catabolic process
G1/S transition of mitotic cell cycle
kidney development
lactation
response to xenobiotic stimulus
organ regeneration
cellular response to insulin stimulus
maternal process involved in female pregnancy
cellular response to xenobiotic stimulus
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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